Why is benzocaine not soluble in water




















Sign In with Email. Remember Me Forgot Password? Benzoic Acid belongs to a class of simple aromatic carboxylic acid. This name is adopted from gum benzoin [The benzoin term in gum benzoin refers to, a tree which is native to the tropical reaches of South-eastern Asia, China, and Indonesia].

Benzoic Acid and its esters occur in apricots, cranberries, mushrooms and jasmine plants. In animal species, benzoic acid is present as part of hippuric acid - in urine of mammals Hippuric Acid: G. The history of benzoic acid dates back to the sixteenth century. In the year Salkowski a prominent scientist discovered its antifungal abilities. The primary reason benzoic acid dissolves only slightly or poorly in cold water is that, because of a polar carboxylic group, the bulk amount of the benzoic acid molecule is non-polar.

It is only the carboxylic group that is polar. Now let us know about how benzoic acid is manufactured and its applications. Manufacturing Process:. Benzoic acid can be attained commercially by partial oxidation of toluene solvent with the help of oxygen.

This process is catalyzed by cobalt or manganese naphthenates catalysts. In the laboratory process benzoic acid is either added directly or created from reactions with its sodium, potassium, or calcium salt. Approximately , tons of benzoic acid is synthesized synthetically each year for use in a large variety of industries. Benzoic acid can be prepared by oxidation process of benzyl chloride in the presence of alkaline potassium permanganate:.

Benzoic acid is mainly dissipated in the production of phenol. Benzoic acid and its salts are mainly used as food preservatives. Benzoic acid inhibits the growth of mold, yeast and some bacteria. It is also a constituent of Whitfield's ointment which is used for the treatment of fungal skin diseases like tinea, ringworm, and athlete's foot. Benzoic acid was used as an expectorant, analgesic, and antiseptic in the early 20th century. Benzoic acid is present as one of the major ingredient that is common in many types of skin care products.

It often suffers from mistaken identity with the name of benzoyl peroxide substance which is a very similar name to it. It is soluble in alcohol or hydrocarbons. This is an important fact to be considered when developing a topical cream or ointment using these as an ingredient. Benzocaine is also used in some oral numbing products. Although rare, Methemoglobinemia can result from high blood concentrations in individuals who have certain risk factors.

This is the reason why it is important when developing a topical skin product with Benzocaine there must be FDA approval before the product goes to market.

If used properly, Benzocaine continues to be a very useful ingredient in topical skin itch and numbing products around the world. RND Center Inc. We strive to get our customers the lowest price possible.



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